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10.3389/fnins.2017.00731 349 WangW.ArakawaH.WangL.OkoloO.SiedlakS

doi:10.3389/fendo.2021.660381 Caputo M, Bona E, Leone I, et al

Among these, the CRL4 E3 ligase comprised of the scaffold protein CUL4A/B, the catalytic subunit RBX1 and the adaptor protein DDB1

Notably, improvements in TAC/MDA occur even when glycemic indices are unchanged, implying a primary redox effect that may precede metabolic reprogramming