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In general, there is a disruption of the periosteum, the vascular supply between the muscle and periosteum, and the interconnections between muscle and bone [18,19,20,21,22], and there is an elimination of the muscle tension and viscoelasticity direct effects [18]

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Animal and in vitro experiments have further verified its barrier repair effect: Butyrate can promote proliferation and mucin secretion of intestinal epithelial cells (IPECs, Caco-2, HT-29), enhance the expression of tight-junction proteins (ZO-1, Claudin-1, Claudin-2), and maintain colonic mucosal integrity (7682)

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