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However, comprehensive studies comparing various tripeptides and larger peptides are needed to validate these distinctions and fully elucidate their effects on wound healing efficacy

As a consequence, a loss of lipoic acid-dependent enzymatic activity caused by defects in endogenous lipoic acid synthesis (see Deficiency) cannot be rescued by the provision of exogenous lipoic acid (5)

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Many are confined to a re-discussion of Nrf2 and HDAC inhibition, lacking integration with its biosynthetic origins and failing to synthesize the rapidly expanding body of evidence on novel and underappreciated mechanisms