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Houthi attacks targeting export ports in Hadramout and Shabwa in late 2022 made shipping and insurance companies more wary of handling Yemeni crude, pushing up insurance costs and weakening buyers willingness to enter into contracts

Beyond-use dating : The period for which a reconstituted solution may be stored and used is defined by the SmPC and local pharmacy policy not by generic rules

Foremost among these is the incomplete understanding of long-term toxicity, biodistribution, and clearance, which raises ongoing concerns regarding in vivo safety [103, 174]