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It seems unlikely that such genes play direct roles in tobacco alkaloid accumulation and their DEG status is likely the result of the fact that the ERF189 and ERF199 transcription factors regulate the expression of gene categories besides those involved in alkaloid biosynthesis (Supplemental Fig

Always prioritize sample evaluation

The CLOZUK study conducted GWAS analysis through GCTA (Genome-wide Complex Trait Analysis) software (19), which could control for family and population structure, and sex

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