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Vapour 2 Review The e-cigarette industry began with the small, cigarette-shaped e-cigarettes that many people today call cig-a-likes. The first cig-a-likes tended to be unreliable, as the disposable plastic cartridges contained little e-liquid, and the filler material wicked e-liquid poorly and was prone to melting

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66,67 Therefore, miRNAs should not be seen as independent diagnostic markers, but rather as possible parts of multi-marker panels that may better reflect OA heterogeneity, including inflammatory phenotypes that may be more common in smoking-related disease