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The common mechanisms of toxicity included promotion of oxidative stress and genotoxicity

Charles father, George V, and grandfather, Edward VII, also died of smoking-related diseases, as did his granduncle Edward VIII, the Duke of Windsor

At the time, it was clear he was in spiritual mood but, now, to find that it was also in his final video, wearing a similar outfit which he had never worn before it is just another example of how Bowie continually transformed himself and changed his directions