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The nuumi integrated program, which combines a CBT-based mobile application with guided nicotine tapering, reported a 7-day point prevalence abstinence rate of 32.4% at 24 weeks , substantially higher than unaided attempts (Source: Implications for Harm Reduction and Public Health Population-level models suggest that complete substitution of cigarettes with ENDS , followed by structured nicotine reduction, can substantially reduce exposure to carbon monoxide and tobacco-specific nitrosamines

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