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Thyroid Gland: Anatomy disease or other autoimmune disease (e.g., pernicious anemia Pernicious anemia A megaloblastic anemia occurring in children but more commonly in later life, characterized by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin B12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor

It can cause wrinkles, fine lines, uneven skin tone, pigmentation, freckles and lack of skin elasticity

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