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Several studies have shown that endothelial function assessed by biomarkers for endothelial function including circulating levels of nitrate/nitrite, NO, von Willebrand factor (vWF), cellular adhesion molecules, vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1), endothelial progenitor cells (EPCs) and endothelial microparticles (EMPs), endothelin-1 and activity of endothelial NOS (eNOS) other than physiological assessment for endothelial function was impaired in smokers

This announcement comes on the heels of the 2020 FDA flavor ban that left menthol products on the market

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This finding was confirmed by another study as well.56 (See below for more information on concept flavors.) In Ontario, Canada, which implemented a ban on menthol cigarettes in 2017, researchers reviewed menthol cigarette sales before and after implementation of the ban