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Behavioral measurements should primarily include the percentage of time spent in the open quadrant, the percentage of entries into the open quadrant, the number of times the animal peeks down from the edge of the platform while in the open or closed quadrant, and the number of stretch-attend postures from the closed quadrant to the open quadrant

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The eligibility of each identified study was evaluated by screening the title, abstract, and full text following the inclusion and exclusion criteria

From a structural point of view, metallo-salens are aromatic metal complexes derived from the condensation of salicylaldehyde with a primary diamine