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A safe cigarette that can both satisfy smokers' demands for taste and nicotine delivery and placate public health concerns is the Holy Grail of the tobacco industry

While its likely the industry will try for a cigar bar exemption again next session in 2026, for now, Montana advocates are celebrating this years defeat alongside key wins, including the passage of legislation that updates the Montana CIAA to include e-cigarettes and vape products in smokefree protections

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The importance of this mechanism was highlighted by studies where supplementation with BH 4 improved endothelium-dependent vasorelaxation in chronic smokers [37] and in isolated blood vessels [38]