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As of the final CDC reporting date (18 February 2020), there were a total of 2,807 hospitalised EVALI cases or deaths reported nationwide, including 68 deaths (CDC 2020)
As a result, their prolonged exposure to environmental stressors like cigarette smoke can trigger chronic stress responsesaltering their behavior, hormone levels, and ultimately, their mental and physical health
The primary challenge was the extreme rarity of PNECs, which make up less than 1% of lung cells, making them nearly impossible to isolate and study in depth, Zhang says