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Dimensions: 3600 x 2400 px | 30.5 x 20.3 cm | 12 x 8 inches | 300dpi Date taken: 12 September 2016 More information: SINGAPORE - CIRCA SEPTEMBER, 2016: cigarettes on display at a store in Singapore Changi Airport

It might be surprising that the downregulation of HIF-1 under normoxic conditions had downstream effects on target gene expression and glycolysis in the present study because HIF-1 is usually considered a hypoxia-regulated transcription factor