-methyltryptophan (-MT) can act as an inhibitor on SLC6A14, which is overexpressed in cells of pancreatic cancer, ER-positive breast cancer, colon cancer, and cervical cancer [34]
Standard protocols are once daily, typically at bedtime on an empty stomach (at least two hours after the last meal), to align with the natural overnight growth hormone pulse window
Pica can result in a variety of adverse effects, such as elevated liver tests (in the case of consuming baking powder), hyperkalaemia, gastrointestinal disturbances (e.g., obstruction, perforation), contamination (e.g., lead or parasites), food displacement, excessive weight gain or hyperglycaemia (0.5 cup corn starch contains 14,240 kcals), metabolic alkalosis (one box of baking soda per day) and dental complications
The effects of GLP-1 receptor agonists on growth and development in children and adolescents have not been fully characterized, and the long-term safety profile in pediatric populations remains unknown
