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Hypoxia-induced stabilization of HIF1a leads to up-regulation of CXCL12, which in turn mediates recruitment of CXCR4-expressing endothelial progenitor cells from the bone marrow, thereby contributing to vasculogenesis [207]

Inhibits melanin production, resulting in lightening of the skin, as well as prevents visible signs of ageing of the skin -like fine lines, hydration and elasticity, given its powerful endogenous antioxidant properties

Potential Benefits Visceral fat reduction: Meaningful reduction in visceral adipose tissue, measurable after about 36 months in HIV-associated lipodystrophy [3]

10.1016/j.redox.2022.102313 Redox Biol