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Importantly, excessive B12 intake is not harmful, as the body excretes any surplus it doesn't need

31 Tips for safer colchicine use: 8, 26, 28 Prescribe the lowest effective dose and provide clear instructions on how and when to take it Advise patients to stop taking colchicine and seek medical attention if they experience nausea, vomiting, diarrhoea or abdominal pain Limit prescriptions to the anticipated number of tablets required for managing an acute attack of gout

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However, it is generally recommended to store them in a cool, dry place, away from heat, moisture, and light