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Low levels of this vital antioxidant have been linked to various health conditions, including cardiovascular diseases, neurodegenerative disorders like Alzheimers and Parkinsons, and even certain cancers

Under prolonged or severe UPR conditions, three transmembrane ER proteinsPERK, IRE1 and ATF6become activated, promoting the upregulation of pro-apoptotic factors, including CHOP (Chen et al., 2023b)

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The cysteine residues (Cys20 and Cys106) of OsDHAR were sulfonylated in the absence of sulfiredoxin ( ScSRX ) under oxidative conditions (Supplemental Fig