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statistics prior to 1995 are not available on the BRFSS web page

Circuit rejected the argument that, because e-cigarettes are claimed to be less risky to the individual than other tobacco products, they should be subject to less stringent authorization through the premarket review process

Details for each outcome on the search string used in the systematic review approach, refined inclusion and exclusion criteria, data extraction template and PRISMA diagram are given in Supplementary Information 1

Regulatory Impact and Challenges The regulatory environment presents both hurdles and opportunities for manufacturers and suppliers