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For example, following diet-induced weight loss, increases can be seen in levels of ghrelin, and gastric inhibitory polypeptide with decreases in levels of leptin, amylin, insulin, PYY, CCK, and glucagon-like peptide-1

2026 Feb:235:111753

In addition, rather than leading to an increase in rT3 levels directly caused by an imbalance in DIO3, the available data imply that Se deficit may indirectly cause these levels to rise via reduced clearance of DIO1 and changes in peripheral thyroid hormone metabolism [33]

Notably, rosavin and salidroside are regarded as key marker compounds for standardization, with salidroside demonstrating significant neuroprotective and antidepressant effects in both preclinical and clinical research