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The 2004 Bissett study in International Journal of Cosmetic Science used twice-daily 5 percent niacinamide for 12 weeks in 50 women aged 40 to 60, documenting significant reductions in fine lines, hyperpigmentation spots, blotchiness, and yellowing [13]

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Furthermore, oxidative stress can enhance the expression of matrix metalloproteinases (MMPs), enzymes that degrade the extracellular matrix and facilitate tumor invasion and metastasis [116]

Stomach acid is essential for breaking down protein into amino acids