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It may take some trial and error to find the one that can improve overall cognitive function

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If human trials reveal minimal systemic absorption after oral dosing, the peptide's utility for GERD would be limited to topical esophageal application or parenteral routes, both of which present practical barriers for chronic reflux management

Nonetheless, the alternative for transposing the intestinal barrier has been the utilization of glutamine dipeptides [2], such as l-alanyl-l-glutamine (DIP), due to the higher stability during heat sterilization and storage and higher solubility compared to free glutamine [139]