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[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Abd El Aziz M., Cahyadi O., Meier J.J., Schmidt W.E., Nauck M.A

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A substantial body of research links elevated IGF-1 activity and IGF-1R signaling to the proliferation and survival of many tumor types, and epidemiological studies have associated higher circulating IGF-1 with increased risk of certain cancers