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International Forum of Allergy & Rhinology 3 (10), 834840 (2013)

Here we show that a genetically encoded tool based on a di-domain glycerol-3-phosphate dehydrogenase from the alga Chlamydomonas reinhardtii ( Cr GPDH) effectively operates both the alternative Gro3P shunt, which regenerates NAD while converting DHAP to Gro3P, and the glycerol shunt, which converts Gro3P to glycerol and inorganic phosphate, across transformed and primary mammalian cell cultures as well as mouse liver

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Full details are published in Organic Process Research & Development .