Dysbiosis during this transition underlies elevated ketosis risk: the decline of VFA-producing taxaincluding Ruminococcus , Prevotella , Selenomonas , and Succinivibrionaceaeimpairs propionate fermentation pathways and reduces gluconeogenic precursor supply, while the concurrent expansion of opportunistic taxa such as Mycoplasma and Saccharimonas further destabilizes ruminal homeostasis (Table 2), collectively contributing to hypoglycemia, excessive mobilization of body fat, and ketone accumulation, which compromise lactation, reproductive performance, and offspring health 47,55,56,57
When evaluating Canadian suppliers, look for Certificate of Analysis (COA) documentation showing purity of 95% or higher, along with heavy metal and endotoxin testing results
doi: 10.1371/journal.pone.0123454 Stupnisek M, Franjic S, Drmic D, et al
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