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Other proteins that bind KEAP1 and interfere with KEAP1-NRF2 interaction, promoting NRF2 accumulation and function in the nucleus, include: phosphoglycerate mutase 5 (PGAM5, a serine/threonine phosphatase related to the phosphoglycerate mutase family), which has been reported to be associated with mitochondria, so its interaction with KEAP1 may be regulated by mitochondrial signalling processes [187, 188]

Glutathione is also critically important to the immune system

Slightly more MEHP leached from PVC 48d compared to PVC 24d , due to the higher initial MEHP content ( p = 2.95 10 5 , Table S2.4) in PVC 48d

Immunohistochemistry As described 62 , tissue sections (10 m) were mounted on glass slides