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When to Seek Medical Advice About B12 Levels Knowing when to consult your GP about vitamin B12 concernswhether related to deficiency or potential excessensures appropriate investigation and management whilst avoiding unnecessary anxiety

The clinical need must be considered in addition to any potential adverse outcomes for the infant

Antidote for methotrexate toxicity and as rescue therapy

The hypothalamus requires adequate energy reserves to maintain the pulsatile secretion of gonadotrophin-releasing hormone (GnRH), which stimulates the pituitary gland to produce luteinising hormone (LH) and follicle-stimulating hormone (FSH)