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Metabolic homeostasis and the cellular redox systems are delicate systems that differ in subcellular compartments and depend on the physiological condition of the animal/cell (e.g., circadian rhythm, cell cycle stage, disease pathology)

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635 The ameliorative benefit of zinc supplements in diabetics can be summarized as the potential hypoglycemic effect of zinc, beneficial modulation of concomitant metabolic aberrations and impaired anti-oxidant status, and attenuation of renal lesions