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(3) In naturally aged mice, FOXO4-DRI treatment reduced senescent cell burden, improved liver and kidney function, restored exercise tolerance (grip strength and running capacity), and improved coat appearanceall markers of healthier aging

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Bootstrap model weighting and averaging of BMDL and BMDU bounds of the 95%CI of BMD for (A-C) 5% prevalence of proteinuria and (D-F) 5% prevalence of low eGFR

The instant a needle penetrates the rubber stopper, three things happen: air enters the vial headspace, the sterile barrier is permanently breached, and the multi-dose use clock starts