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Consider B12 injections if oral supplements cause discomfort

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employed in osteoarthritis and cartilage regeneration research Pigs Used for pharmacokinetic profiling and oral bioavailability studies Cynomolgus monkeys 9-month chronic toxicology studies via oral gavage Human subjects Approximately 900 participants across six clinical trials examining safety and efficacy Research Limitations & Regulatory Status Critical Gaps in Current Evidence Despite over 25 years of research and extensive clinical testing, AOD-9604 faces substantial evidence gaps that have prevented therapeutic development

Cytoprotection and Anti-Inflammation It reduces pro-inflammatory cytokines (e.g., TNF-, IL-6) and oxidative stress, protecting tissues from chronic inflammatory damage