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By inhibiting NNMT, 5-Amino-1MQ prevents the methylation of nicotinamide, allowing more substrate to enter the NAD+ salvage pathway

Target site identification and proposing an alternate spray use criteria All sinuses, except sphenoid, drain into the ostiomeatal complex (OMC), it being the main mucociliary drainage pathway and airflow exchange corridor between the nasal airway and the adjoining sinus cavities

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It is a small molecule that works by inhibiting the activity of an enzyme called nicotinamide N-methyltransferase (NNMT)