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Several RCTs on other immune-related conditions, including fibromyalgia, rheumatoid arthritis, and multiple sclerosis, supported the immunomodulatory effects of supplementation [138,139,140,141,142]

We also found that GH application in the presence of TTX and synaptic blockers depolarized 25% of ARH AgRP neurons (3 out 12 recorded cells from 4 mice), changing in +7.7 1.4 mV their resting membrane potential ( t (2) = 5.277, P = 0.0341)

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