Furthermore, studies have found that in high-glucose-cultured human dermal fibroblasts, treatment with secretory autophagosomes derived from Human Umbilical Vein Endothelial Cells (HUVECs) can reduce endoplasmic reticulum stress-regulated free Fe generation, while increasing fibroblast exosome release to export free Fe, thereby inhibiting ferroptosis and restoring fibroblast proliferation and migration functions
Hepatocellular Responses, Cellular Degeneration, Injury, and Death Introduction The function and structure of most liver cells are relatively constrained by their genetic programs of metabolism, differentiation, and specialization
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Sadr-Azodi O, Sanders DS, Murray JA, Ludvigsson JF