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This neurotransmitters release is coupled to the endocytosis of SV to preserve the SV pool for the normal functioning of the synapse

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In 2011, the transmembrane glycoprotein CD44, a cancer stem-like cell marker, and more precisely the CD44 variant (CD44 v ) capable to bind hyaluronan has also been described to interacts and stabilizes system (Figure 1)

This is why we always begin with a careful assessmentincluding imaging and orthopedic consultation when neededto determine whether peptides are a helpful adjunct or if other treatments must come first