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The homologous cytochrome CYP2A6 of humans in Cyp2a5 mice is expressed in several liver diseases by the induction of toxic chemicals [77], where the levels of mRNA and Cyp2a5, on comparison between knockout NRF-2/ and wild-type mice, proved the increase of NRF-2 and Cyp2a5 in wild-type mice, as well as their interaction by co-immunoprecipitation Cyp controlled by NRF-2 [77]

Glutathione Glutathione (GSH) is a low molecular weight thiol tripeptide (-glutamyl-cysteinyl-glycine) abundant in almost all cellular compartments (in the nucleus, mitochondria, and cytoplasm)

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