Neurobiology of Aging 32 (5): 763777
Co-expression network reveals the potential relationship between glutathione with DEGs and DEMs In addition to core genes and metabolites of glutathione metabolism KEGG pathway, 6 DEGs ( cgs1 , 100381533 , bHLH11 , AR7 , OHP2 , MatE, abc1 ) and 5 DEMs (1,3-Benzodioxol-5-yl(oxo)acetic acid, dihydroplumbagin, 6-(2-methoxy-Z-vinyl)-7-methyl-pyranocoumarin, (7R)-(+)-Lyoniresinol 9-glucoside, and Capsanthin-3,6-epoxide) derived from co-expression network those were potentially involved in glutathione metabolism
Abbreviations ASM, antiseizure medication
We also know that high levels of human growth hormone over a long period can produce irreversible acromegaly, the complications of which include arthritis, sleep apnoea, diabetes, high blood pressure, heart disease and often premature death