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Per CMS Billing and Coding Article A56681 and Medicare LCD coverage criteria, the primary ICD-10-CM codes supporting medical necessity for CPT 64483 include M54.16 (radiculopathy, lumbar region), M54.17 (radiculopathy, lumbosacral), M48.061 (spinal stenosis, lumbar with neurogenic claudication), M47.816 (spondylosis with radiculopathy, lumbar), and M51.16 (intervertebral disc degeneration, lumbar)
This should be accounted for in research designs that include oral glucose tolerance tests or mixed meal tolerance tests, as retatrutides pharmacodynamic effects will blunt the glycemic response independent of changes in fasting glucose or insulin sensitivity
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