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[13] [14] In higher plants, SOD isozymes have been localized in different cell compartments

LPS/TLR4 signal transduction pathway

Oral pathogens, especially P.g , can upregulate hepatic flavin-containing monooxygenase 3 (FMO3) through their derived products and promote the conversion of TMA to TMAO, while simultaneously disrupting the intestinal barrier and disturbing the gut microbiota structure, forming an oralgutliver pathogenic pathway (Wang et al., 2024

Of the three amino acids involved in glutathione production, glutamate, cysteine, and glycine, cysteine is usually considered to be the limiting resource (Meister).FIG