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The FDA started cracking down on peptides in 2024 and 2025, sending warning letters to dozens of clinics, pharmacies, and websiteseven the ones saying "research only." The heat is only rising

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Even with preservatives, repeatedly dipping a dropper into the vial after touching your face introduces skin floraStaphylococcus epidermidis, Cutibacterium acnesthat secrete proteases

For instance, reversed were increased number of inflammatory cells (38, 44-46) and the rise of leukotriene B4 (LTB4), thromboxane B2 (TXB2), and myeloperoxidase (MPO) in the serum and inflamed tissues (47-49)