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Vitamin B12 plays a role in producing brain chemicals, such as serotonin, that help control mood and other brain functions

When the intracellular tight junctions do not function optimally, the intestinal mucosa becomes more permeable or leaky, leading to the vicious cycle of inflammation and dysfunction known as leaky gut syndrome, or increased intestinal permeability

Similar content being viewed by others Introduction T2DM and MASLD, two closely intertwined metabolic disorders rooted in insulin resistance, have become major global public health challenges in the management of chronic metabolic diseases

Brain 123 , 585590 (2000)