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42 Panduratin A is highly lipophilic 18 and tends to be distributed in the tissue rather than circulating in the blood vessels

Infection Any IV carries an infection risk if hygiene is poor

Copper and ceruloplasmin levels assess copper status

48, 72 We further found that in colonic epithelial cells subjected to colitis causing chemical (DSS treatment), claudin-2 expression is sharply downregulated and that constitutive claudin-2 expression in these cells protected them from DSS-induced cell death