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Interestingly, cysteine deprivation and activation of necroptosis are associated with the augmented activity of glutaminolysis [231], which fuels the mitochondrial Krebs cycle through the conversion of glutamate to -ketoglutarate [232]

Hepatology 68(1):234247

[325] Alcohol can also affect the ocular surface, with some studies suggesting a link to DED and increased tear osmolarity, while others show contradictory results