Omega-3 Fatty Acids: Building Blocks for Brain Function Omega-3 fatty acids, particularly docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are essential fats critical for brain development and function
Otto C, Kaemmerer U, Illert B, Muehling B, Pfetzer N, Wittig R et al
In addition, CCL2 and CCL5 are considered to be the two main chemokines of TAMs, which responsible for attracting TAMs infiltration and inducing its polarization towards the oncogenic M2 phenotype whereas blocking CCL2 and CCL5 can block the occurrence of this phenomenon (52, 53), such as the mRNA encoding BisCCL2/5i encapsulated in a lipid nanoparticle platform can block both CCL2 and CCL5 signaling thereby significantly inducing TAMs to the anti-tumor M1 phenotype polarization and reversing immunosuppression in the TME (54)
Step 2: Preparation for the Procedure Once cleared for treatment, preparation for the injection involves: Hydration: Patients are often advised to hydrate well before the procedure to assist with detoxification