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Clashes between protein and lipid atoms were reduced through 2500 conjugate-gradient minimization steps, followed by a 6 ns long MD simulation with a linearly-released positional constraint of 1 kcal mol 1 2 on protein and lipid phosphorus atoms

Notably, ingestion in the fasting state markedly increases EGCG bioavailability and amplifies hepatotoxic risk, prompting regulatory mandates for warning labels on supplement packaging