In the nucleus, following heterodimer complex formation with transcription factors, like small Maf proteins (G/F/K) and c-Jun, Nrf2 complexes bind to the antioxidant response element (ARE), a regulatory enhancer region within gene promoters that upregulate antioxidant and anti-inflammatory defense processes (Cuadrado et al., 2019
The infrastructure for visible regrowth is building
Herzog K, Ijlst L, van Cruchten AG, van Roermund CWT, Kulik W, Wanders RJA, Waterham HR (2019) An UPLC-MS/MS assay to measure glutathione as marker for oxidative stress in cultured cells
That said, pairing with recovery support like DHEA or ZMT can improve hormonal balance post-cycle for enhanced sleep, libido, and stress resilience