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The extremely limited modern clinical trial database means DSIP remains far from any therapeutic application

Li-mei Yu, [email protected] These authors have contributed equally to this work This article was submitted to Multiple Sclerosis and Neuroimmunology, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

To explain the dependence of slime secretion on the presence of secretins, we consider two plausible mechanisms: secretins could either be directly involved in slime secretion as the OM gates through which the synthesized polymer is secreted, or indirectly by secreting enzymes that then polymerize slime on the cell surface, similar to the synthesis of bacterial dextranes 30

BJP-IVb reduces iron content to prevent PD by inhibiting iron regulatory protein in dopaminergic neurons