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However, variations arising from production conditions and potential contamination with heavy metals or other toxic elements underscore the need for rigorous quality control and standardized cultivation and extraction practices

GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine, originally isolated by Loren Pickart from human plasma in 1973. The compound is one of the most extensively characterized small peptides in published research, with documented effects on collagen synthesis, glycosaminoglycan production, and approximately 4,000 human gene expression changes

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doi: 10.1038/s41418-020-00728-1 52 HouYCaiSYuSLinH