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There's enough anecdote data about people talking about addictions

10.1016/j.seizure.2017.08.002 17

The methods used to establish improvement were not adequately standardised by modern withdrawal-assessment criteria

Accelerated approval for Filspari was granted based on data from the Phase III PROTECT study, which showed that the small molecule blocker lowered urine protein levels more than three times as much as the active control, Avapro