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Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses

Depending on the balance between ROS and the availability of antioxidants in the microenvironment of the cell, antioxidants can inhibit or delay the initiation or propagation of oxidative chain reaction and thus prevent or repair cell damage caused by reactive oxygen [8]

For patients with DIE, characterized by fibrotic, deeply invasive lesions often involving bowel, bladder, or uterosacral ligaments, fertility impairment results from both mechanical distortion and an inflammatory microenvironment

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