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XG-102 administered to healthy male volunteers as a single intravenous infusion: a randomized, double-blind, placebo-controlled, dose-escalating study

Glutathione plays a crucial role in neutralizing harmful free radicals, detoxifying the body, and supporting a healthy immune system

It catalyzes the reduction of glutathione from the oxidized form of GS-SG, and all other enzymes of the glutathione system use it: 2 NADP + GS-SG 2 NADP + 2 GSH The reduction of oxidized glutathione is carried out with the participation of NADP + reduction systems on the pentose phosphate pathway of glucose-6-phosphate oxidation ("Embden-Meyerhoff shunt"): NADP + + G-6-P NADP + + + 6 phosphogluconate Glutathione transferase catalyzes the reaction: RX + GSH = HX + GS-SG Some forms of glutathione transferases, like glutathione peroxidases, are capable of reducing lipid hydroperoxides to hydroxy acids (LOH) [12]